Gene SPCS3
Description Signal peptidase complex subunit 3
Protein isoforms1 P61009
HPA2 Intracellular
SPC score3 1

log2( Protein abundance )cISUP grade groups Non-cancercISUP1cISUP2cISUP3cISUP4cISUP5161820222426
Pre- vs Post-DRE Pre-DRE_P20Post-DRE_P2016182022


Dataset Samples Peptides Median log2 Protein abundance ICC4
uEV-P20 100 (66.2%) 4 (4) 21.03

1 - The UniProt Consortium
UniProt: the Universal Protein Knowledgebase in 2023
Nucleic Acids Res. 51:D523–D531 (2023)

2 - The Human Protein Atlas
Uhlén M, Karlsson MJ, Hober A, Svensson AS, Scheffel J, Kotol D, Zhong W, Tebani A, Strandberg L, Edfors F, Sjöstedt E, Mulder J, Mardinoglu A, Berling A, Ekblad S, Dannemeyer M, Kanje S, Rockberg J, Lundqvist M, Malm M, Volk AL, Nilsson P, Månberg A, Dodig-Crnkovic T, Pin E, Zwahlen M, Oksvold P, von Feilitzen K, Häussler RS, Hong MG, Lindskog C, Ponten F, Katona B, Vuu J, Lindström E, Nielsen J, Robinson J, Ayoglu B, Mahdessian D, Sullivan D, Thul P, Danielsson F, Stadler C, Lundberg E, Bergström G, Gummesson A, Voldborg BG, Tegel H, Hober S, Forsström B, Schwenk JM, Fagerberg L, Sivertsson Å. Sci Signal. 2019 Nov 26;12(609):eaaz0274. doi: 10.1126/scisignal.aaz0274. PMID: 31772123

3 - SurfaceGenie
Waas M, Snarrenberg ST, Littrell J, Jones Lipinski RA, Hansen P, Corbett JA, Gundry RL, SurfaceGenie: A web-based application for prioritizing cell-type specific marker candidates, Bioinformatics, 2020, PMID: 32053146

4 - Intraclass coefficient (ICC): The proportion of inter-individual variance relative to total intra- and inter-individual variance explained by a linear mixed-effects model