Gene SORT1
Description Sortilin
Protein isoforms1 Q99523
Q99523-2
HPA2 Membrane
SPC score3 2

log2( Protein abundance )cISUP grade groups Non-cancercISUP1cISUP2cISUP3cISUP4cISUP512141618202224
Pre- vs Post-DRE Pre-DREPost-DRE16182022


Dataset Samples Peptides Median log2 Protein abundance ICC4
uSP 143 (95.3%) 13 (13) 19.2 0.5431
uEV-P20 23 (15.2%) 3 (3) 16.7
uEV-P150 39 (25.5%) 6 (6) 16.45

1 - The UniProt Consortium
UniProt: the Universal Protein Knowledgebase in 2023
Nucleic Acids Res. 51:D523–D531 (2023)

2 - The Human Protein Atlas
Uhlén M, Karlsson MJ, Hober A, Svensson AS, Scheffel J, Kotol D, Zhong W, Tebani A, Strandberg L, Edfors F, Sjöstedt E, Mulder J, Mardinoglu A, Berling A, Ekblad S, Dannemeyer M, Kanje S, Rockberg J, Lundqvist M, Malm M, Volk AL, Nilsson P, Månberg A, Dodig-Crnkovic T, Pin E, Zwahlen M, Oksvold P, von Feilitzen K, Häussler RS, Hong MG, Lindskog C, Ponten F, Katona B, Vuu J, Lindström E, Nielsen J, Robinson J, Ayoglu B, Mahdessian D, Sullivan D, Thul P, Danielsson F, Stadler C, Lundberg E, Bergström G, Gummesson A, Voldborg BG, Tegel H, Hober S, Forsström B, Schwenk JM, Fagerberg L, Sivertsson Å. Sci Signal. 2019 Nov 26;12(609):eaaz0274. doi: 10.1126/scisignal.aaz0274. PMID: 31772123

3 - SurfaceGenie
Waas M, Snarrenberg ST, Littrell J, Jones Lipinski RA, Hansen P, Corbett JA, Gundry RL, SurfaceGenie: A web-based application for prioritizing cell-type specific marker candidates, Bioinformatics, 2020, PMID: 32053146

4 - Intraclass coefficient (ICC): The proportion of inter-individual variance relative to total intra- and inter-individual variance explained by a linear mixed-effects model