Gene APP
Description Amyloid beta A4 protein
Protein isoforms1 P05067
P05067-10
P05067-11
P05067-2
P05067-3
P05067-4
P05067-5
P05067-6
P05067-7
P05067-8
P05067-9
HPA2 Vesicles
SPC score3 3



Dataset Samples Peptides Median log2 Protein abundance ICC4
uSP 150 (100.0%) 24 (23) 22.64 0.6642
uEV-P20 132 (87.4%) 20 (19) 20.18 0.1948
uEV-P150 123 (80.4%) 12 (11) 17.86 0.3961

1 - The UniProt Consortium
UniProt: the Universal Protein Knowledgebase in 2023
Nucleic Acids Res. 51:D523–D531 (2023)

2 - The Human Protein Atlas
Uhlén M, Karlsson MJ, Hober A, Svensson AS, Scheffel J, Kotol D, Zhong W, Tebani A, Strandberg L, Edfors F, Sjöstedt E, Mulder J, Mardinoglu A, Berling A, Ekblad S, Dannemeyer M, Kanje S, Rockberg J, Lundqvist M, Malm M, Volk AL, Nilsson P, Månberg A, Dodig-Crnkovic T, Pin E, Zwahlen M, Oksvold P, von Feilitzen K, Häussler RS, Hong MG, Lindskog C, Ponten F, Katona B, Vuu J, Lindström E, Nielsen J, Robinson J, Ayoglu B, Mahdessian D, Sullivan D, Thul P, Danielsson F, Stadler C, Lundberg E, Bergström G, Gummesson A, Voldborg BG, Tegel H, Hober S, Forsström B, Schwenk JM, Fagerberg L, Sivertsson Å. Sci Signal. 2019 Nov 26;12(609):eaaz0274. doi: 10.1126/scisignal.aaz0274. PMID: 31772123

3 - SurfaceGenie
Waas M, Snarrenberg ST, Littrell J, Jones Lipinski RA, Hansen P, Corbett JA, Gundry RL, SurfaceGenie: A web-based application for prioritizing cell-type specific marker candidates, Bioinformatics, 2020, PMID: 32053146

4 - Intraclass coefficient (ICC): The proportion of inter-individual variance relative to total intra- and inter-individual variance explained by a linear mixed-effects model